Información del producto
CDK5 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
CDK5
Research Area
Neuroscience, Cell Division and Proliferation, Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
cyclin-dependent kinase 5
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Cyclin-dependent kinase 5|Cell division protein kinase 5|Cyclin-dependent-like kinase 5|Serine/threonine-protein kinase PSSALRE|Tau protein kinase II catalytic subunit (TPKII catalytic subunit)|CDK5|CDKN5|PSSALRE
Host
Rabbit
UniProt ID
Q00535
Gene ID
1020
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
33 kDa
Background
Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and D3-type G1 cyc
phosphorylates the linker domain of glutamyl-prolyl tRNA synthetase(EPRS) in a IFN-gamma-dependent manner, the initial event in assembly of the GAIT complex. Phosphorylation of SH3GLB1 is required for autophagy induction in starved neurons. Phosphorylatio
synaptic vesicle exocytosis, vesicles fusion with the presynaptic membrane, and endocytosis. Promotes cell survival by activating anti-apoptotic proteins BCL2 and STAT3, and negatively regulating of JNK3/MAPK10 activity. Phosphorylation of p53/TP53 in res
phosphorylates the linker domain of glutamyl-prolyl tRNA synthetase(EPRS) in a IFN-gamma-dependent manner, the initial event in assembly of the GAIT complex. Phosphorylation of SH3GLB1 is required for autophagy induction in starved neurons. Phosphorylatio
synaptic vesicle exocytosis, vesicles fusion with the presynaptic membrane, and endocytosis. Promotes cell survival by activating anti-apoptotic proteins BCL2 and STAT3, and negatively regulating of JNK3/MAPK10 activity. Phosphorylation of p53/TP53 in res