Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IF, FC
Target
CD80
Research Area
Immunology, Cardiovascular, Signal Transduction
Form
liquid
Recomended Dilution
IF: 1:20-1:200
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
CD80 molecule
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
T-lymphocyte activation antigen CD80|Activation B7-1 antigen|BB1|CTLA-4 counter-receptor B7.1 (B7)|CD80|CD28LG|CD28LG1|LAB7
Host
Rabbit
UniProt ID
P33681
Gene ID
941
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
60 kDa
Background
(Microbial infection) Acts as a receptor for adenovirus subgroup B.
Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.