Información del producto
CD46 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IP
Target
CD46
Research Area
Immunology, Metabolism
Form
liquid
Recomended Dilution
IP: 1:200-1:1000
WB: 1:500-1:1000
WB: 1:500-1:1000
Type Clonality
polyclonal
Immunogen
CD46 molecule, complement regulatory protein
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Membrane cofactor protein|TLX|Trophoblast leukocyte common antigen|CD46|MCP|MIC10
Host
Rabbit
UniProt ID
P15529
Gene ID
4179
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
50-56 kDa
Background
(Microbial infection) A number of viral and bacterial pathogens seem to bind MCP in order to exploit its immune regulation property and directly induce an immunosuppressive phenotype in T-cells. Acts as a receptor for adenovirus subgroup B2 and Ad3, cultu
Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fert
Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fert