Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IHC
Target
CD244
Research Area
Immunology, Signal Transduction
Form
liquid
Recomended Dilution
IHC: 1:20-1:200
Type Clonality
polyclonal
Immunogen
CD244 molecule, natural killer cell receptor 2B4
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Natural killer cell receptor 2B4|NK cell activation-inducing ligand (NAIL)|NK cell type I receptor protein 2B4 (NKR2B4, h2B4)|SLAM family member 4 (SLAMF4)|Signaling lymphocytic activation molecule 4|CD244|2B4
Host
Rabbit
UniProt ID
Q9BZW8
Gene ID
51744
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Background
Heterophilic receptor of the signaling lymphocytic activation molecule(SLAM) family
expression on activated T-cells and binding to CD488 provides costimulatory-like function for neighboring T-cells(By similarity). Inhibits inflammatory responses in dendritic cells(DCs)(By similarity).
its ligand is CD48. SLAM receptors triggered by homo-or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and a