Información del producto
CASP4 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
CASP4
Research Area
Metabolism
Form
liquid
Recomended Dilution
IF: 1:50-1:500
IHC: 1:20-1:200
WB: 1:200-1:2000
IHC: 1:20-1:200
WB: 1:200-1:2000
Type Clonality
polyclonal
Immunogen
caspase 4, apoptosis-related cysteine peptidase
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Caspase-4 (CASP-4)|ICE and Ced-3 homolog 2 (ICH-2)|ICE(rel)-II|Mih1|Protease TX|Caspase-4 subunit p10|Caspase-4 subunit p20|CASP4|ICH2
Host
Rabbit
UniProt ID
P49662
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
43 kDa
Background
Inflammatory caspase, essential effector of NLRP3 inflammasome-dependent CASP1 activation and IL1B and IL18 secretion in response to non-canonical activators, such as UVB radiation, cholera enterotoxin subunit B and cytosolic LPS(PubMed:22246630, PubMed:2
this activity may not require caspase enzymatic activity(PubMed:26508369). Involved in cell death induced by endoplasmic reticulum stress and by treatment with cytotoxic APP peptides found Alzheimer's patient brains(PubMed:15123740, PubMed:22246630, PubMe
this activity may not require caspase enzymatic activity(PubMed:26508369). Involved in cell death induced by endoplasmic reticulum stress and by treatment with cytotoxic APP peptides found Alzheimer's patient brains(PubMed:15123740, PubMed:22246630, PubMe