Información del producto
C1QBP antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IF
Target
C1QBP
Research Area
Immunology, Cardiovascular
Form
liquid
Recomended Dilution
IF: 1:20-1:200
IHC: 1:20-1:200
WB: 1:500-1:2000
IHC: 1:20-1:200
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
complement component 1, q subcomponent binding protein
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Complement component 1 Q subcomponent-binding protein, mitochondrial|ASF/SF2-associated protein p32|Glycoprotein gC1qBP (C1qBP)|Hyaluronan-binding protein 1|Mitochondrial matrix protein p32|gC1q-R protein|p33 (SF2AP32)|C1QBP|GC1QBP|HABP1|SF2P32
Host
Rabbit
UniProt ID
Q07021
Gene ID
708
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
32 kDa
Background
Is believed to be a multifunctional and multicompartmental protein involved in inflammation and infection processes, ribosome biogenesis, regulation of apoptosis, transcriptional regulation and pre-mRNA splicing. At the cell surface is thought to act as a
ligation by HCV core protein is resulting in suppresion of interleukin-12 production in monocyte-derived dendritic cells. Involved in regulation of antiviral response by inhibiting DDX58-and IFIH1-mediated signaling pathways probably involving its associa
may perform the receptor function through a complex with C1qR/CD93. In complex with cytokeratin-1/KRT1 is a high affinity receptor for kininogen-1/HMWK. Can also bind other plasma proteins, such as coagulation factor XII leading to its autoactivation. May
specifically binds to the globular "heads" of C1q thus inhibiting C1
the function may involve the exchange of FBL for RRP1 in the association with pre-ribosome particles. Involved in regulation of RNA splicing by inhibiting the RNA-binding capacity of SRSF1 and its phosphorylation. Is required for the nuclear translocation
the function seems to involve its RNA-binding activity. May be involved in the nucleolar ribosome maturation process
ligation by HCV core protein is resulting in suppresion of interleukin-12 production in monocyte-derived dendritic cells. Involved in regulation of antiviral response by inhibiting DDX58-and IFIH1-mediated signaling pathways probably involving its associa
may perform the receptor function through a complex with C1qR/CD93. In complex with cytokeratin-1/KRT1 is a high affinity receptor for kininogen-1/HMWK. Can also bind other plasma proteins, such as coagulation factor XII leading to its autoactivation. May
specifically binds to the globular "heads" of C1q thus inhibiting C1
the function may involve the exchange of FBL for RRP1 in the association with pre-ribosome particles. Involved in regulation of RNA splicing by inhibiting the RNA-binding capacity of SRSF1 and its phosphorylation. Is required for the nuclear translocation
the function seems to involve its RNA-binding activity. May be involved in the nucleolar ribosome maturation process