Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IF
Target
BLMH
Research Area
Cardiovascular, Metabolism
Form
liquid
Recomended Dilution
IF: 1:20 - 1:50
IHC: 1:50 - 1:200
WB: 1:500 - 1:2000
Type Clonality
polyclonal
Immunogen
bleomycin hydrolase
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Bleomycin hydrolase (BH, BLM hydrolase, BMH)|BLMH
Host
Rabbit
UniProt ID
Q13867
Gene ID
642
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Rat
Observed MW
50 kDa
Background
Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution
however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine p