Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
ATG4D
Research Area
Cardiovascular, Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:1000
Type Clonality
polyclonal
Immunogen
ATG4 autophagy related 4 homolog D
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Cysteine protease ATG4D|AUT-like 4 cysteine endopeptidase|Autophagy-related cysteine endopeptidase 4 (Autophagin-4)|Autophagy-related protein 4 homolog D (HsAPG4D)|Cysteine protease ATG4D, mitochondrial|ATG4D|APG4D|AUTL4
Host
Rabbit
UniProt ID
Q86TL0
Gene ID
84971
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
53 kDa
Background
Cysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of
Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport(Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the