Información del producto
BMAL1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IP, IHC, WB
Target
BMAL1
Research Area
Neuroscience, Cardiovascular, Metabolism, Signal Transduction
Form
liquid
Recomended Dilution
IHC: 1:50-1:500
IP: 1:200-1:1000
WB: 1:500-1:1000
IP: 1:200-1:1000
WB: 1:500-1:1000
Type Clonality
polyclonal
Immunogen
aryl hydrocarbon receptor nuclear translocator-like
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Basic helix-loop-helix ARNT-like protein 1|Aryl hydrocarbon receptor nuclear translocator-like protein 1|Basic-helix-loop-helix-PAS protein MOP3|Brain and muscle ARNT-like 1|Class E basic helix-loop-helix protein 5 (bHLHe5)|Member of PAS protein 3|PAS dom
Host
Rabbit
UniProt ID
O00327
Gene ID
406
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
69-75 kDa
Background
Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expres
regulates glucose-stimulated insulin secretion via the regulation of antioxidant genes NFE2L2/NRF2 and its targets SESN2, PRDX3, CCLC and CCLM. Negatively regulates the mTORC1 signaling pathway
regulates the expression of MTOR and DEPTOR. Controls diurnal oscillations of Ly6C inflammatory monocytes
rhythmic recruitment of the PRC2 complex imparts diurnal variation to chemokine expression that is necessary to sustain Ly6C monocyte rhythms. Regulates the expression of HSD3B2, STAR, PTGS2, CYP11A1, CYP19A1 and LHCGR in the ovary and also the genes invo
regulates glucose-stimulated insulin secretion via the regulation of antioxidant genes NFE2L2/NRF2 and its targets SESN2, PRDX3, CCLC and CCLM. Negatively regulates the mTORC1 signaling pathway
regulates the expression of MTOR and DEPTOR. Controls diurnal oscillations of Ly6C inflammatory monocytes
rhythmic recruitment of the PRC2 complex imparts diurnal variation to chemokine expression that is necessary to sustain Ly6C monocyte rhythms. Regulates the expression of HSD3B2, STAR, PTGS2, CYP11A1, CYP19A1 and LHCGR in the ovary and also the genes invo