Gene DescriptionFas (TNF receptor superfamily, member 6)
Storage ConditionsStore at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
SpecificityR-125224 binds to the extracellular portion of human Fas at an eptiope consisting of the sequence RTQNTKCRCK (aa 105-114) (pmid: 11754745). Fas is a type I membrane protein which belongs to the tumor necrosis factor (TNF) receptor/nerve growth factor (NGF
Application KeyWB,IF,Flow Cyt
FormLiquid
Recomended DilutionFlow cytometry Immunofluorescence Western Blot The optimal working dilution should be determined by the end user.
Antigen species Target speciesHuman
ImmunogenOriginal antibody is raised against by the humanization of the murine HFE7A anti-Fas antibody by grafting the CDR regions to the framework regions of the human 8E10 antibody and substituting key framework residues from the murine antibody into the 8E10 se