Storage Conditions
-20°C/1 year
Applications
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300,WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Recombinant Protein of ATG7
Subcellular Location
Cytoplasm . Preautophagosomal structure . Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
10533
Observed Band
78kD
Other Name
APG7-like
Autophagy-related protein 7
Ubiquitin-activating enzyme E1-like protein)
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7
hAGP7
Background
This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associate