Storage Conditions
-20°C/1 year
Applications
ELISA
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
ELISA 2000-20000
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human PDHK1 (Phospho Tyr243)
Subcellular Location
Mitochondrion matrix .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
5163
Observed Band
50kD
Other Name
Pyruvate dehydrogenase kinase isoform 1)
[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial (EC 2.7.11.2
Background
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic acti