Información del producto
CFTR (Phospho-Ser737) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
IF
IHC
WB
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-200, WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human CFTR (Phospho-Ser737)
Subcellular Location
Apical cell membrane
Multi-pass membrane protein . Cell membrane
Multi-pass membrane protein . Early endosome membrane
Multi-pass membrane protein . Endoplasmic reticulum membrane
Multi-pass membrane protein . Nucleus . The channel is internalized from the cell surface into an endosomal recycling compartment, from where it is recycled to the cell membrane (PubMed:17462998, PubMed:19398555, PubMed:20008117). In the oviduct and bronc
Multi-pass membrane protein . Recycling endosome membrane
Multi-pass membrane protein . Cell membrane
Multi-pass membrane protein . Early endosome membrane
Multi-pass membrane protein . Endoplasmic reticulum membrane
Multi-pass membrane protein . Nucleus . The channel is internalized from the cell surface into an endosomal recycling compartment, from where it is recycled to the cell membrane (PubMed:17462998, PubMed:19398555, PubMed:20008117). In the oviduct and bronc
Multi-pass membrane protein . Recycling endosome membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
1080
Observed Band
166kD
Other Name
ATP-binding cassette sub-family C member 7
Channel conductance-controlling ATPase
Cystic fibrosis transmembrane conductance regulator (CFTR
EC 3.6.3.49
cAMP-dependent chloride channel)
Channel conductance-controlling ATPase
Cystic fibrosis transmembrane conductance regulator (CFTR
EC 3.6.3.49
cAMP-dependent chloride channel)
Background
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP