Storage Conditions
-20°C/1 year
Applications
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-200, WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human ITK AA range: 450-530
Subcellular Location
Cytoplasm . Nucleus . Localizes in the vicinity of cell surface receptors in the plasma membrane after receptor stimulation.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
3702
Observed Band
72kD
Other Name
IL-2-inducible T-cell kinase
Interleukin-2-inducible T-cell kinase
Kinase EMT
T-cell-specific kinase
Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2
Tyrosine-protein kinase Lyk)
Background
This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by R