Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 ELISA 1:5000-20000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from part region of human protein AA range: 400-500
Subcellular Location
Single-pass type I membrane protein . Apical cell membrane
Single-pass type I membrane protein . Isoform 1 shedding leads to a soluble peptide. .
[Isoform 1]: Cell membrane
[Isoform 2]: Secreted .
[Klotho peptide]: Secreted .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
9365
Observed Band
111kD
Background
This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (