Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 ELISA 1:5000-20000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human protein . at AA range: 120-200
Subcellular Location
Cell membrane
Multi-pass membrane protein.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
2826
Observed Band
39kD
Background
CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900])
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chem
MIM 604833)
the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27