Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 ELISA 1:5000-20000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from part region of human protein
Subcellular Location
[Isoform 1]: Cytoplasm . Golgi apparatus. Cell membrane . Endoplasmic reticulum. Early endosome membrane. Late endosome membrane. Cell projection, phagocytic cup . Localized to the plasma membrane as a result of myristoylation. Phosphorylation on Ser-16 l
[Isoform 2]: Endoplasmic reticulum. Early endosome membrane. Late endosome membrane. Translocates to late endosomes upon LPS stimulation where it colcoalizes with isoform 1.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
100302736
Observed Band
25kD
Background
MIM 147810) (TIR) domain-containing adaptor protein involved in Toll receptor signaling (see TLR4
MIM 603030).[supplied by OMIM, Apr 2004],
TIRP is a Toll/interleukin-1 receptor (IL1R