NFE2 rabbit pAb
  • NFE2 rabbit pAb
ELK

NFE2 rabbit pAb

Ref: ELK-ES10767-100μL
100μL

Información del producto

Información adicional
Storage Conditions -20°C/1 year
Applications ELISA
WB
Concentration 1 mg/ml
Recomended Dilution WB 1:500-2000 ELISA 1:5000-20000
Type Clonality Polyclonal
Immunogen Synthesized peptide derived from part region of human protein
Subcellular Location Nucleus, PML body. Cytoplasm. The sumoylated form locates to the nuclear bodies PML oncogenic domains (PODs). Translocated to the cytoplasm through interaction with ITCH.
Iso type IgG
Tissue Source Rabbit
Reactivity Human
Mouse
Rat
Human Gen 4778
Observed Band 41kD
Background function:Required for activity at the locus control region (LCR) upstream of the globin gene complexes. Requires p18 NF-E2 for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production: globin synthesis, heme synthesis, and the p
leading to activate transcription of the beta-globin locus (By similarity). Heterodimer of p45 NF-E2 and p18 NF-E2. Forms high affinity heterodimer with MAFG
the interaction promotes erythropoiesis.,tissue specificity:Expressed in hematopoietic cells and also in colon and testis.,