Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human Granzyme B Polyclonal AA range: 81-130
Subcellular Location
Secreted . Cytolytic granule . Delivered into the target cell by perforin (PubMed:20038786). .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
3002
Observed Band
38kD
Other Name
C11
CTLA-1
CTSGL1
Cathepsin G-like 1
Cytotoxic T-lymphocyte proteinase 2
Fragmentin-2
Granzyme-2
Granzyme B (EC 3.4.21.79
HLP
Human lymphocyte protein
Lymphocyte protease
SECT
T-cell serine protease 1-3E)
Background
This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to g