Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human TIE2 Polyclonal
Subcellular Location
Cell membrane
Single-pass type I membrane protein. Cell junction . Cell junction, focal adhesion . Cytoplasm, cytoskeleton. Secreted . Recruited to cell-cell contacts in quiescent endothelial cells (PubMed:18425120, PubMed:18425119). Colocalizes with the actin cytoskel
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
7010
Observed Band
120kD
Other Name
Angiopoietin-1 receptor (EC 2.7.10.1
CD antigen CD202b)
Endothelial tyrosine kinase
Tunica interna endothelial cell kinase
Tyrosine-protein kinase receptor TEK
Tyrosine-protein kinase receptor TIE-2
Tyrosine kinase with Ig and EGF homology domains-2
hTIE2
p140 TEK
Background
This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fib