Información del producto
IGF1R (Phospho-Tyr1161) Rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000, ELISA 1:10000-20000
Type Clonality
Polyclonal
Immunogen
Synthesized phospho derived from human IGF1R (Phospho-Tyr1161)
Subcellular Location
Cell membrane
Single-pass type I membrane protein .
Single-pass type I membrane protein .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
3480
Observed Band
pro: 155kD, recetor beta: 95kD
Other Name
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain
Insulin-like growth factor 1 receptor beta chain]
Insulin-like growth factor 1 receptor beta chain]
Background
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It