Información del producto
Stat3 (Acetyl Lys87) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IHC
WB
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
ELISA 2000-20000
IHC-p 1:50-300
WB 1:500-2000
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized acetyl-peptide derived from human Stat3 around the acetylation site of K87.
Subcellular Location
Cytoplasm . Nucleus . Shuttles between the nucleus and the cytoplasm. Translocated into the nucleus upon tyrosine phosphorylation and dimerization, in response to signaling by activated FGFR1, FGFR2, FGFR3 or FGFR4. Constitutive nuclear presence is indepe
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
6774
Observed Band
85kD
Other Name
APRF
Acute-phase response factor
STAT3
Signal transducer and activator of transcription 3
Acute-phase response factor
STAT3
Signal transducer and activator of transcription 3
Background
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the ce