Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from NHERF-2 . at AA range: 20-100
Subcellular Location
Endomembrane system
Peripheral membrane protein . Nucleus . Apical cell membrane . Localizes with EZR and PODXL at the apical cell membrane of glomerular epithelium cells and the sides of the food processes (By similarity). Nuclear, in a punctate pattern. .
Peripheral membrane protein . Nucleus . Apical cell membrane . Localizes with EZR and PODXL at the apical cell membrane of glomerular epithelium cells and the sides of the food processes (By similarity). Nuclear, in a punctate pattern. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
9351
Observed Band
37kD
Other Name
NHE3 kinase A regulatory protein E3KARP
NHERF-2
NHERF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2
SIP-1
SLC9A3R2
SRY-interacting protein 1
Sodium-hydrogen exchanger regulatory factor 2
Solute carrier family 9 isoform A3 regulatory factor 2
TKA-1
Tyrosine kinase activator protein 1
NHERF-2
NHERF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2
SIP-1
SLC9A3R2
SRY-interacting protein 1
Sodium-hydrogen exchanger regulatory factor 2
Solute carrier family 9 isoform A3 regulatory factor 2
TKA-1
Tyrosine kinase activator protein 1
Background
This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins.