Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human USP45. AA range:301-350
Subcellular Location
Photoreceptor inner segment . Cytoplasm . Nucleus .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
85015
Observed Band
90kD
Other Name
Deubiquitinating enzyme 45
USP45
Ubiquitin-specific-processing protease 45
Ubiquitin carboxyl-terminal hydrolase 45
Ubiquitin thioesterase 45
USP45
Ubiquitin-specific-processing protease 45
Ubiquitin carboxyl-terminal hydrolase 45
Ubiquitin thioesterase 45
Background
The protein encoded by this gene is a deubiquitylase that binds ERCC1, the catalytic subunit of the XPF-ERCC1 DNA repair endonuclease. This endonuclease is a critical regulator of DNA repair processes, and the deubiquitylase activity of the encoded protei