Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human BCAR3. AA range:761-810
Subcellular Location
Cytoplasm . Cell junction, focal adhesion . Localization to focal adhesions depends on interaction with PTPRA. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
8412
Observed Band
92kD
Other Name
BCAR3
Breast cancer anti-estrogen resistance protein 3
NSP2
Novel SH2-containing protein 2
SH2 domain-containing protein 3B
SH2D3B
Background
breast cancer anti-estrogen resistance 3(BCAR3) Homo sapiens Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estroge