Información del producto
TRF1 (phospho Ser219) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Telomeric Repeat Binding Factor 1 around the phosphorylation site of Ser219. AA range:185-234
Subcellular Location
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, telomere. Colocalizes with telomeric DNA in interphase and prophase cells. Telomeric localization decreases in metaphase, anaphase and telophase. Associates with the mitotic spindle.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
7013
Observed Band
55kD
Other Name
NIMA-interacting protein 2
PIN2
TERF1
TRBF1
TRF
TRF1
TTAGGG repeat-binding factor 1
Telomeric protein Pin2/TRF1
Telomeric repeat-binding factor 1
PIN2
TERF1
TRBF1
TRF
TRF1
TTAGGG repeat-binding factor 1
Telomeric protein Pin2/TRF1
Telomeric repeat-binding factor 1
Background
This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of