Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human BRCA2. AA range:31-80
Subcellular Location
Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Colocalizes with ERCC5/XPG to nuclear foci following DNA replication stress. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Rat
Rat
Human Gen
675
Other Name
BRCA2
Breast cancer type 2 susceptibility protein
FACD
FANCD1
Fanconi anemia group D1 protein
Breast cancer type 2 susceptibility protein
FACD
FANCD1
Fanconi anemia group D1 protein
Background
Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-st