Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human SPTBN1. AA range:651-700
Subcellular Location
Cytoplasm, cytoskeleton . Cytoplasm, myofibril, sarcomere, M line . Colocalizes with ANK2 in a distinct intracellular compartment of neonatal cardiomyocytes. .
Cytoplasmic side .
Peripheral membrane protein
[Isoform 2]: Cell membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
6711
Observed Band
275kD
Other Name
Beta-II spectrin
Fodrin beta chain
SPTB2
SPTBN1
Spectrin, non-erythroid beta chain 1
Spectrin beta chain
non-erythrocytic 1
Background
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is compo