Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human RyR2. AA range:2774-2823
Subcellular Location
Multi-pass membrane protein . Membrane
Multi-pass membrane protein . Sarcoplasmic reticulum . The number of predicted transmembrane domains varies between orthologs, but both N-terminus and C-terminus seem to be cytoplasmic. .
Sarcoplasmic reticulum membrane
Multi-pass membrane protein . Sarcoplasmic reticulum . The number of predicted transmembrane domains varies between orthologs, but both N-terminus and C-terminus seem to be cytoplasmic. .
Sarcoplasmic reticulum membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
6262
Observed Band
200-300kD
Other Name
Cardiac muscle ryanodine receptor
Cardiac muscle ryanodine receptor-calcium release channel
RYR-2
RYR2
RyR2
Ryanodine receptor 2
Type 2 ryanodine receptor
hRYR-2
Cardiac muscle ryanodine receptor-calcium release channel
RYR-2
RYR2
RyR2
Ryanodine receptor 2
Type 2 ryanodine receptor
hRYR-2
Background
This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B