Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ARRDC3. AA range:365-414
Subcellular Location
Cytoplasm . Cell membrane
Cytoplasmic side . Lysosome . Endosome . Early endosome . Associated with plasma membrane, as well as with endosomes and lysosomes during endocytosis (PubMed:16269462, PubMed:23208550, PubMed:20559325). .
Peripheral membrane protein
Cytoplasmic side . Lysosome . Endosome . Early endosome . Associated with plasma membrane, as well as with endosomes and lysosomes during endocytosis (PubMed:16269462, PubMed:23208550, PubMed:20559325). .
Peripheral membrane protein
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
57561
Observed Band
46kD
Other Name
ARRDC3
Arrestin domain-containing protein 3
KIAA1376
TBP-2-like inducible membrane protein
TLIMP
Arrestin domain-containing protein 3
KIAA1376
TBP-2-like inducible membrane protein
TLIMP
Background
This gene encodes a member of the arrestin family of proteins, which regulate G protein-mediated signaling. The encoded protein is thought to act as a regulator of breast cancer growth and progression by binding to a phosphorylated form of integrin beta4,