Storage Conditions
-20°C/1 year
Applications
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human INTS2. AA range:201-250
Subcellular Location
Nucleus membrane
Single-pass membrane protein . Cytoplasm .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
57508
Observed Band
140kD
Other Name
INTS2
Int2
Integrator complex subunit 2
KIAA1287
Background
INTS2 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A
MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1
MIM 180680) and U2 (RNU2
MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008],