Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
IHC
WB
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from the Internal region of human PKN.
Subcellular Location
Cytoplasm . Nucleus . Endosome . Cell membrane
Peripheral membrane protein . Cleavage furrow . Midbody . Associates with chromatin in a ligand-dependent manner. Localization to endosomes is mediated via its interaction with RHOB. Association to the cell membrane is dependent on Ser-377 phosphorylation
Peripheral membrane protein . Cleavage furrow . Midbody . Associates with chromatin in a ligand-dependent manner. Localization to endosomes is mediated via its interaction with RHOB. Association to the cell membrane is dependent on Ser-377 phosphorylation
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
5585
Observed Band
105kD
Other Name
PAK-1
PAK1
PKN
PKN1
PRK1
PRKCL1
Protease-activated kinase 1
Protein-kinase C-related kinase 1
Protein kinase C-like 1
Protein kinase C-like PKN
Protein kinase PKN-alpha
Serine-threonine protein
Serine/threonine-protein kinase N1
PAK1
PKN
PKN1
PRK1
PRKCL1
Protease-activated kinase 1
Protein-kinase C-related kinase 1
Protein kinase C-like 1
Protein kinase C-like PKN
Protein kinase PKN-alpha
Serine-threonine protein
Serine/threonine-protein kinase N1
Background
protein kinase N1(PKN1) Homo sapiens The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activa