Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IP
WB
IF
IP
WB
Concentration
1 mg/ml
Recomended Dilution
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MBTPS2. AA range:301-350
Subcellular Location
Membrane
Multi-pass membrane protein . Cytoplasm .
Multi-pass membrane protein . Cytoplasm .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
51360
Other Name
Endopeptidase S2P
MBTPS2
Membrane-bound transcription factor site-2 protease
S2P
SREBPs intramembrane protease
Sterol regulatory element-binding proteins intramembrane protease
MBTPS2
Membrane-bound transcription factor site-2 protease
S2P
SREBPs intramembrane protease
Sterol regulatory element-binding proteins intramembrane protease
Background
IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.[provided by RefSeq, Aug 2009],
This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been as
This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been as