AZ1 rabbit pAb
  • AZ1 rabbit pAb
ELK

AZ1 rabbit pAb

Ref: ELK-ES6440-50ul
50ul

Información del producto

Información adicional
Storage Conditions -20°C/1 year
Applications ELISA
IF
IHC
WB
Concentration 1 mg/ml
Recomended Dilution Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000,WB 1:500-2000
Type Clonality Polyclonal
Immunogen The antiserum was produced against synthesized peptide derived from human OAZ1. AA range:14-63
Subcellular Location nucleus,cytoplasm,cytosol,
Iso type IgG
Tissue Source Rabbit
Reactivity Human
Mouse
Rat
Human Gen 4946
Other Name OAZ
OAZ1
ODC-Az
Ornithine decarboxylase antizyme 1
Background The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which i
and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms
thus, completing the auto-regulatory circuit. This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradatio