Información del producto
Neuregulin-1 SMDF rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human NRG1 isoform-10. AA range:1-50
Subcellular Location
Single-pass type I membrane protein. Does not seem to be active.
Single-pass type I membrane protein. May possess an internal uncleaved signal sequence.
[Isoform 8]: Nucleus. May be nuclear.
[Isoform 9]: Secreted. Has a signal peptide.
[Isoform 10]: Membrane
[Neuregulin-1]: Secreted.
[Pro-neuregulin-1, membrane-bound isoform]: Cell membrane
Single-pass type I membrane protein. May possess an internal uncleaved signal sequence.
[Isoform 8]: Nucleus. May be nuclear.
[Isoform 9]: Secreted. Has a signal peptide.
[Isoform 10]: Membrane
[Neuregulin-1]: Secreted.
[Pro-neuregulin-1, membrane-bound isoform]: Cell membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
3084
Observed Band
44kD
Other Name
GGF
HGL
HRGA
NDF
NRG1
Pro-NRG1
Pro-neuregulin-1 membrane-bound isoform
SMDF
HGL
HRGA
NDF
NRG1
Pro-NRG1
Pro-neuregulin-1 membrane-bound isoform
SMDF
Background
The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene thr