Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
IHC
WB
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from Lck BP-1 . at AA range: 340-420
Subcellular Location
Membrane
Peripheral membrane protein . Cytoplasm . Mitochondrion .
Peripheral membrane protein . Cytoplasm . Mitochondrion .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
3059
Observed Band
54kD
Other Name
HCLS1
HS1
Hematopoietic cell-specific LYN substrate 1
Hematopoietic lineage cell-specific protein
LckBP1
p75
HS1
Hematopoietic cell-specific LYN substrate 1
Hematopoietic lineage cell-specific protein
LckBP1
p75
Background
developmental stage:Expressed in early stage of myeloid and erythroid differentiation.,function:Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells.
rapidly after cross-linking of surface IgM on B-cells.,similarity:Contains 1 SH3 domain.,similarity:Contains 4 cortactin repeats.,subunit:Associates with the SH2 and SH3 domains of LCK. Binding to he LCK SH3 domain occurs constitutively, while binding to
rapidly after cross-linking of surface IgM on B-cells.,similarity:Contains 1 SH3 domain.,similarity:Contains 4 cortactin repeats.,subunit:Associates with the SH2 and SH3 domains of LCK. Binding to he LCK SH3 domain occurs constitutively, while binding to