Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human HtrA2. AA range:116-165
Subcellular Location
Mitochondrion intermembrane space. Mitochondrion membrane
Single-pass membrane protein . Predominantly present in the intermembrane space. Released into the cytosol following apoptotic stimuli, such as UV treatment, and stimulation of mitochondria with caspase-8 truncated BID/tBID.
[Isoform 1]: Endoplasmic reticulum .
Single-pass membrane protein . Predominantly present in the intermembrane space. Released into the cytosol following apoptotic stimuli, such as UV treatment, and stimulation of mitochondria with caspase-8 truncated BID/tBID.
[Isoform 1]: Endoplasmic reticulum .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
27429
Observed Band
45-50kD
Other Name
HTRA2
High temperature requirement protein A2
HtrA2
OMI
Omi stress-regulated endoprotease
PRSS25
Serine protease 25
Serine protease HTRA2
Serine proteinase OMI
mitochondrial
High temperature requirement protein A2
HtrA2
OMI
Omi stress-regulated endoprotease
PRSS25
Serine protease 25
Serine protease HTRA2
Serine proteinase OMI
mitochondrial
Background
This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release