Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from the C-terminal region of human β-1,4-Gal-T1.
Subcellular Location
Single-pass type II membrane protein. Cell membrane
Single-pass type II membrane protein. Cell surface . Cell projection, filopodium . Found in trans cisternae of Golgi but is mainly localized at the plasma membrane (PubMed:1714903). B4GALT1 cell surface expression is regulated by UBE2Q1 (By similarity). .
Single-pass type II membrane protein. Found in trans cisternae of Golgi. .
[Isoform Long]: Golgi apparatus, Golgi stack membrane
[Isoform Short]: Golgi apparatus, Golgi stack membrane
[Processed beta-1,4-galactosyltransferase 1]: Secreted . Soluble form found in body fluids. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
2683
Observed Band
50kD
Other Name
4-galactosyltransferase 1
B4GALT1
Beta-1
Beta-1,4-GalTase 1
Beta4Gal-T1
GGTB2
UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1
UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1
b4Gal-T1
Background
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose
all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-t