Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
WB
IF
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human GABBR1. AA range:891-940
Subcellular Location
Cell membrane
Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane
Multi-pass membrane protein . Cell projection, dendrite . Colocalizes with ATF4 in hippocampal neuron dendritic membranes (By similarity). Coexpression of GABBR1 and GABBR2 is required for GABBR1 maturation and transport to the plasma membrane (PubMed:156
[Isoform 1E]: Secreted .
Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane
Multi-pass membrane protein . Cell projection, dendrite . Colocalizes with ATF4 in hippocampal neuron dendritic membranes (By similarity). Coexpression of GABBR1 and GABBR2 is required for GABBR1 maturation and transport to the plasma membrane (PubMed:156
[Isoform 1E]: Secreted .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Guinea pig
Human
Mouse
Rat
Human
Mouse
Rat
Human Gen
2550
Observed Band
108kD
Other Name
GABA-B-R1
GABA-BR1
GABA-B receptor 1
GABABR1
GABBR1
GPRC3A
Gamma-aminobutyric acid type B receptor subunit 1
Gb1
GABA-BR1
GABA-B receptor 1
GABABR1
GABBR1
GPRC3A
Gamma-aminobutyric acid type B receptor subunit 1
Gb1
Background
This gene encodes a receptor for gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. This receptor functions as a heterodimer with GABA(B) receptor 2. Defects in this gene may underlie bra