Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IF
Concentration
1 mg/ml
Recomended Dilution
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human DARC. AA range:1-50
Subcellular Location
Early endosome. Recycling endosome. Membrane
Multi-pass membrane protein. Predominantly localizes to endocytic vesicles, and upon stimulation by the ligand is internalized via caveolae. Once internalized, the ligand dissociates from the receptor, and is targeted to degradation while the receptor is
Multi-pass membrane protein. Predominantly localizes to endocytic vesicles, and upon stimulation by the ligand is internalized via caveolae. Once internalized, the ligand dissociates from the receptor, and is targeted to degradation while the receptor is
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
2532
Other Name
CD antigen CD234
DARC
Duffy antigen/chemokine receptor
FY
Fy glycoprotein
GPD
Glycoprotein D
GpFy
Plasmodium vivax receptor
DARC
Duffy antigen/chemokine receptor
FY
Fy glycoprotein
GPD
Glycoprotein D
GpFy
Plasmodium vivax receptor
Background
The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this ge