Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ZNRF2. AA range:161-210
Subcellular Location
Endosome membrane
Peripheral membrane protein .
Peripheral membrane protein . Cell junction, synapse, presynaptic cell membrane
Peripheral membrane protein . Lysosome membrane
Peripheral membrane protein .
Peripheral membrane protein . Cell junction, synapse, presynaptic cell membrane
Peripheral membrane protein . Lysosome membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
223082
Other Name
E3 ubiquitin-protein ligase ZNRF2
Protein Ells2
RING finger protein 202
RNF202
ZNRF2
Zinc/RING finger protein 2
Protein Ells2
RING finger protein 202
RNF202
ZNRF2
Zinc/RING finger protein 2
Background
domain:The RING-type zinc finger domain is required for E3 ligase activity.,function:May play a role in the establisment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from
protein ubiquitination.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 RING-type zinc finger.,subcellular location:Present in presynaptic plasma membranes in neurons.,subunit:Interacts with UBE2N.,tissue specificity:High
protein ubiquitination.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 RING-type zinc finger.,subcellular location:Present in presynaptic plasma membranes in neurons.,subunit:Interacts with UBE2N.,tissue specificity:High