Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from Eme1 . at AA range: 250-330
Subcellular Location
Nucleus, nucleolus . Recruited to regions of DNA damage in S-phase cells.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
146956
Observed Band
65kD
Other Name
Crossover junction endonuclease EME1
EME1
MMS4
MMS4 homolog
hMMS4
Background
This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures an