Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ME3. AA range:545-594
Subcellular Location
Mitochondrion matrix.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
10873
Observed Band
67kD
Other Name
ME3
Malic enzyme 3
NADP-ME
NADP-dependent malic enzyme
mitochondrial
Background
Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent is