Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human BST2. AA range:101-150
Subcellular Location
Golgi apparatus, trans-Golgi network. Cell membrane
Golgi apparatus, trans-Golgi network . Late endosome . (Microbial infection) HIV-1 VPU and HIV-2 ENV can target it to the trans-Golgi network thus sequestering it away from virus assembly sites on the cell membrane. Targeted to late endosomes upon KSHV in
Lipid-anchor, GPI-anchor . Membrane raft. Cytoplasm. Apical cell membrane . Shuttles between the cell membrane, where it is present predominantly in membrane/lipid rafts, and the trans-Golgi network. Forms a complex with MMP14 and localizes to the cytopla
Single-pass type II membrane protein. Cell membrane
Golgi apparatus, trans-Golgi network . Late endosome . (Microbial infection) HIV-1 VPU and HIV-2 ENV can target it to the trans-Golgi network thus sequestering it away from virus assembly sites on the cell membrane. Targeted to late endosomes upon KSHV in
Lipid-anchor, GPI-anchor . Membrane raft. Cytoplasm. Apical cell membrane . Shuttles between the cell membrane, where it is present predominantly in membrane/lipid rafts, and the trans-Golgi network. Forms a complex with MMP14 and localizes to the cytopla
Single-pass type II membrane protein. Cell membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
684
Observed Band
20kD
Other Name
BST-2
BST2
Bone marrow stromal antigen 2
CD317
HM1.24 antigen
Tetherin
BST2
Bone marrow stromal antigen 2
CD317
HM1.24 antigen
Tetherin
Background
Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined
however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis. [provided by RefSeq, Jul 2008],
however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis. [provided by RefSeq, Jul 2008],