Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the N-terminal region of human SERPINA1. AA range:1-50
Subcellular Location
Secreted. Endoplasmic reticulum. The S and Z allele are not secreted effectively and accumulate intracellularly in the endoplasmic reticulum.
[Short peptide from AAT]: Secreted, extracellular space, extracellular matrix.
[Short peptide from AAT]: Secreted, extracellular space, extracellular matrix.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
5265
Observed Band
47kD
Other Name
AAT
Alpha-1 protease inhibitor
Alpha-1-antiproteinase
Alpha-1-antitrypsin
PI
SERPINA1
Serpin A1
Alpha-1 protease inhibitor
Alpha-1-antiproteinase
Alpha-1-antitrypsin
PI
SERPINA1
Serpin A1
Background
The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcr