Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IF: 1:50-200 WB 1:500-2000, ELISA 1:10000-20000 IHC 1:50-300
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from the Internal region of human AR.
Subcellular Location
Nucleus . Cytoplasm . Detected at the promoter of target genes (PubMed:25091737). Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of RAC
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
367
Observed Band
99kD
Other Name
AR
Androgen receptor
DHTR
Dihydrotestosterone receptor
NR3C4
Nuclear receptor subfamily 3 group C member 4
Androgen receptor
DHTR
Dihydrotestosterone receptor
NR3C4
Nuclear receptor subfamily 3 group C member 4
Background
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription fact