Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human TNFSF10. AA range:31-80
Subcellular Location
Cell membrane
Single-pass type II membrane protein . Secreted . Exists both as membrane-bound and soluble form. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
8743
Observed Band
33kD
Other Name
APO2L
Apo-2 ligand
Apo-2L
CD253
Protein TRAIL
TNF-related apoptosis-inducing ligand
TNFSF10
TRAIL
Tumor necrosis factor ligand superfamily member 10
Background
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed a