Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from Thrombopoietin receptor at AA range: 321-370
Subcellular Location
Cell membrane
Single-pass type I membrane protein. Golgi apparatus . Cell surface .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
4352
Observed Band
69,40kD
Other Name
CD110
MPL
Myeloproliferative leukemia protein
Proto-oncogene c-Mpl
TPO-R
TPOR
Thrombopoietin receptor
Background
In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the human homologue, named, c-mpl, was cloned. Sequence data re