Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from the N-terminal region of human IDH1.
Subcellular Location
Cytoplasm, cytosol . Peroxisome .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
3417
Observed Band
46kD
Other Name
Cytosolic NADP-isocitrate dehydrogenase
IDH
IDH1
IDP
Isocitrate dehydrogenase [NADP] cytoplasmic
NADP(+)-specific ICDH
Oxalosuccinate decarboxylase
PICD
Background
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases