Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human CD177. AA range:361-410
Subcellular Location
Cell membrane
Lipid-anchor, GPI-anchor . Membrane raft
Lipid-anchor, GPI-like-anchor . Secreted . Cytoplasmic granule membrane . Cell projection, lamellipodium . Cell surface expression on neutrophils is increased upon TNF-alpha, fMLP or CXCL8/IL8-mediated stimulation (PubMed:17244676, PubMed:17580308). In ne
Lipid-anchor, GPI-anchor . Membrane raft
Lipid-anchor, GPI-like-anchor . Secreted . Cytoplasmic granule membrane . Cell projection, lamellipodium . Cell surface expression on neutrophils is increased upon TNF-alpha, fMLP or CXCL8/IL8-mediated stimulation (PubMed:17244676, PubMed:17580308). In ne
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
57126
Observed Band
46kD
Other Name
CD177
CD177
CD177 antigen
HNA-2a
Human neutrophil alloantigen 2a
NB1
NB1 GP
NB1 glycoprotein
PRV-1
PRV1
Polycythemia rubra vera protein 1
CD177
CD177 antigen
HNA-2a
Human neutrophil alloantigen 2a
NB1
NB1 GP
NB1 glycoprotein
PRV-1
PRV1
Polycythemia rubra vera protein 1
Background
This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in